• Card 6 / 24: Watch this video ( http://openstaxcollege.org/l/basalnuclei2 ) to learn about the basal nuclei (also known as the basal ganglia), which have two pathways that process information within the cerebrum. As shown in this video, the indirect pathway is the longer pathway through the system that results in decreased activity in the cerebral cortex, and therefore less motor activity. The indirect pathway has an extra couple of connections in it, including disinhibition of the subthalamic nucleus. What is the end result on the thalamus, and therefore on movement initiated by the cerebral cortex?

    Answer:
    By disinhibiting the subthalamic nucleus, the indirect pathway increases excitation of the globus pallidus internal segment. That, in turn, inhibits the thalamus, which is the opposite effect of the direct pathway that disinhibits the thalamus.

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Anatomy & Physiology 13 Nervous System Anatomy

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Attribution:  OpenStax College. Anatomy & Physiology, OpenStax-CNX Web site. http://cnx.org/content/col11496/1.6/, Jun 11, 2014
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