• Card 12 / 18: Ketone bodies are used as an alternative source of fuel during starvation. Describe how ketones are synthesized.

    Answer:
    When triglycerides and fatty acids are broken down, acetyl CoA is created. If excess acetyl CoA is generated in this process, the excess is used in ketogenesis or the creation of ketones. This creation results from the conversion of acetyl CoA by thiolase into acetoacetyl CoA. This acetoacetyl CoA is subsequently converted into ß-hydroxybutyrate, the most common ketone in the body.

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Anatomy & Physiology 24 Metabolism & Nutrition

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Attribution:  OpenStax College. Anatomy & Physiology, OpenStax-CNX Web site. http://cnx.org/content/col11496/1.6/, Jun 11, 2014
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