Associate Scientist/Scientist, Discovery
Position Summary
We are seeking an Associate Scientist/Scientist, Discovery who will report to our Senior Director, Discovery Biology.
They will be responsible for executing biochemical and cellular assays to support drug discovery efforts.
The ideal candidate will be experienced with the testing of chemical compounds, data analysis and reporting results and conclusions to support lead identification and optimization.
Candidates should be comfortable working in a fast-paced, dynamic, and team-oriented environment.
Responsibilities
Work closely with biology and chemistry teams to design and test novel peptides for non-muscle delivery and advance EDO platform.
Establish cellular and biochemical assays to elucidate the mechanism of action of next-generation peptides in different cellular contexts.
Design and execute biochemical and cell-based high-throughput assays and implement rigorous data analysis techniques to identify lead molecules.
Perform molecular techniques including DNA/RNA isolation, PCR, qRT-PCR, gene expression analysis, cell line engineering and tissue culture as needed.
Identify and characterize target-appropriate cell models for proof-of-concept analysis.
Support assay development, quality control and data handling by CROs.
Collaborate effectively with internal colleagues and effectively communicate data and ideas to team members.
Deliver clear summaries of research findings to Project Review meetings.
Maintain electronic lab notebook, SOPs, appropriate documentation for scientific data and experimental protocols.
Highly motivated scientist with ability to multitask and prioritize work.
Demonstrate ability to thrive in a fast-paced environment.
Directly manage and oversee projects and timelines for associate scientists.
Requirements
Ph.D.
in one of the following:
molecular biology, cell biology, neuroscience, biochemistry with minimum 2+ years of postdoctoral experience in academia or industry settings with some industry experience
Demonstrated experience with in vitro cell-based assay development and execution
Hands-on experience in tissue culture, plate-based assays, RNA isolation, gene expression analysis (qPCR), western blot, ELISA,multiplex protein analysis, flow cytometry preferred
Experience in neuromuscular and/or CNS drug discovery preferred
Experience with hands on and/or managing in vivo work at CROs is a plus
Experience with managing CROs and academic collaborations preferred
Self-motivation, ability to work independently, excellent organization skills, multitasking and working within timelines is required
Ability to learn rapidly, adapt and exercise flexibility for changing platform needs, workflows and projects is required.
Good verbal, written and presentation communication skills, as well as excellent interdisciplinary and interpersonal skills with the ability to work in a team environment.
Familiar with Microsoft Office programs and data analysis software such as GraphPad Prism
Skills:
Project Planning • Project Management • Protein Assays • siRNA • Oligonucleotides • Biomarkers • Assay Development • PCR• Molecular Biology • RNA • Immunoprecipitation • ELISA • miRNA • SIMOA • MSD ELISA
About PepGen
PepGen Inc.
is a clinical-stage biotechnology companyadvancing the next-generation of oligonucleotide therapies with the goal of transforming the treatment of severe neuromuscular and neurological diseases.
PepGen's Enhanced Delivery Oligonucleotide, or EDO, platform is founded on over a decade of research and development and leverages cell-penetrating peptides to improve the uptake and activity of conjugated oligonucleotide therapeutics.
Using these EDO peptides, we are generating a pipeline of oligonucleotide therapeutic candidates that target the root cause of serious diseases.
For more information, visit *** or follow PepGen onTwitterandLinkedIn.
EEO Statement
PepGen is an Equal Opportunity Employer committed to a culturally diverse workforce.
All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status.
Note:
This is an on-site role 5 days/week.
Recruitment & Staffing Agencies
PepGen does not accept unsolicited agency resumes.
Currently, we are working exclusively with The Bowdoin Group for all our recruiting needs.
Thank you.
•
United States - MA - MA - Pittsfield
June 27, 2024
SkyBridge Healthcare Therapy is seeking a travel Physical Therapist for a travel job in Pittsfield, Massachusetts. & Requirements • Specialty: Physical Therapist • Discipline: Therapy • Start Date: 07/22/2024 • Duration: 13 weeks • 40 hours per week • Shift: 8 hours, days • Employment Type: Travel...
United States - MA - MA - Hyde Park
June 12, 2024
Manager, Contract Management The Manager, Contract Management serves as a strategic business partner to our Business Development and Legal organizations. • The Manager, Contract Management will support the development and execution of contracts with new and existing customers ensuring Catalent...
United States - MA - MA - Plymouth
June 27, 2024
CrossMed is seeking a travel nurse RN Labor and Delivery for a travel nursing job in Plymouth, Massachusetts. & Requirements • Specialty: Labor and Delivery • Discipline: RN • Start Date: 07/15/2024 • Duration: 13 weeks • 36 hours per week • Shift: 12 hours • Employment Type: Travel Job Details •...
United States - MA - MA - Plymouth
June 11, 2024
Account Director, Biologics Drug Substance Catalent Biologics is a fast-growing business within Catalent Pharma Solutions focused on providing innovative technologies and solutions to help more and better biologic treatments get to patients. • The business includes our proprietary GPEx cell...
United States - MA - MA - Gardner
June 27, 2024
Aureus Medical Group - Imaging is seeking a travel CT Technologist for a travel job in Gardner, Massachusetts. & Requirements • Specialty: CT Technologist • Discipline: Allied Health Professional • Start Date: ASAP • Duration: 12 weeks • 40 hours per week • Shift: 8 hours • Employment Type: Travel...
United States - MA - MA - Boston
June 27, 2024
Aureus Medical Group - Imaging is seeking a travel Interventional Radiology Technologist for a travel job in Boston, Massachusetts. & Requirements • Specialty: Interventional Radiology Technologist • Discipline: Allied Health Professional • Start Date: ASAP • Duration: 14 weeks • 40 hours per week •...
United States - MA - MA - WINCHESTER
June 27, 2024
AMN Healthcare Allied is seeking a travel CT Technologist for a travel job in WINCHESTER, Massachusetts. & Requirements • Specialty: CT Technologist • Discipline: Allied Health Professional • Start Date: 07/15/2024 • Duration: 13 weeks • 40 hours per week • Shift: 10 hours, nights • Employment Type:...
United States - MA - MA - Arlington Heights
June 27, 2024
We are looking to hire a new Full time Physical Therapists for the Cambridge and Somerville area's. This positions pays up to 130k. At Caretenders, a part of LHC Group, we embrace a culture of caring, belonging, and trust and enjoy the meaningful connections that come from it: for the whole patient,...
United States - MA - MA - Holyoke
June 27, 2024
Epic Travel Staffing is seeking a travel nurse RN Psychiatric for a travel nursing job in Holyoke, Massachusetts. & Requirements • Specialty: Psychiatric • Discipline: RN • Start Date: 07/15/2024 • Duration: 13 weeks • 40 hours per week • Shift: 8 hours, nights • Employment Type: Travel Job...
United States - MA - MA - South Weymouth
June 27, 2024
QS Nurses is seeking a travel nurse RN CCU - Coronary Care for a travel nursing job in South Weymouth, Massachusetts. & Requirements • Specialty: CCU - Coronary Care • Discipline: RN • Start Date: 07/29/2024 • Duration: 12 weeks • 36 hours per week • Shift: 12 hours, nights • Employment Type: Travel...
GHR Healthcare Travel Division
United States - MA - MA - Attleboro
June 27, 2024
GHR Healthcare - Travel Division is seeking a travel nurse RN Med Surg / Telemetry for a travel nursing job in Attleboro, Massachusetts. & Requirements • Specialty: Med Surg / Telemetry • Discipline: RN • Start Date: 07/15/2024 • Duration: 13 weeks • 36 hours per week • Shift: 12 hours, nights •...
United States - MA - MA - Medford
June 27, 2024
We are looking to hire a new Full time Physical Therapists for the Cambridge and Somerville area's. This positions pays up to 130k. At Caretenders, a part of LHC Group, we embrace a culture of caring, belonging, and trust and enjoy the meaningful connections that come from it: for the whole patient,...
United States - MA - MA - Charlton
May 21, 2024
Role Overview The purpose of this position is to provide hands-on engineering support to the operations to produce high quality medical devices. This position will lead continuous improvement activities, implement and document manufacturing processes, devise engineering solutions to manufacturing...
United States - MA - MA - Newtonville
June 27, 2024
We are looking to hire a new Full time Physical Therapists for the Cambridge and Somerville area's. This positions pays up to 130k. At Caretenders, a part of LHC Group, we embrace a culture of caring, belonging, and trust and enjoy the meaningful connections that come from it: for the whole patient,...
United States - MA - MA - Ludlow
June 12, 2024
Manager, Contract Management The Manager, Contract Management serves as a strategic business partner to our Business Development and Legal organizations. • The Manager, Contract Management will support the development and execution of contracts with new and existing customers ensuring Catalent...
United States - MA - MA - Gardner
June 27, 2024
Magnet Medical is seeking a travel CT Technologist for a travel job in Gardner, Massachusetts. & Requirements • Specialty: CT Technologist • Discipline: Allied Health Professional • Start Date: ASAP • Duration: 13 weeks • 36 hours per week • Shift: 12 hours, nights • Employment Type: Travel Magnet...
United States - MA - MA - Reading
June 12, 2024
Manager, Contract Management The Manager, Contract Management serves as a strategic business partner to our Business Development and Legal organizations. • The Manager, Contract Management will support the development and execution of contracts with new and existing customers ensuring Catalent...
United States - MA - MA - Mattapan
June 11, 2024
Account Director, Biologics Drug Substance Catalent Biologics is a fast-growing business within Catalent Pharma Solutions focused on providing innovative technologies and solutions to help more and better biologic treatments get to patients. • The business includes our proprietary GPEx cell...
United States - MA - MA - Brookline Village
June 27, 2024
We are looking to hire a new Full time Physical Therapists for the Cambridge and Somerville area's. This positions pays up to 130k. At Caretenders, a part of LHC Group, we embrace a culture of caring, belonging, and trust and enjoy the meaningful connections that come from it: for the whole patient,...
United States - MA - MA - Allston
June 27, 2024
We are looking to hire a new Full time Physical Therapists for the Cambridge and Somerville area's. This positions pays up to 130k. At Caretenders, a part of LHC Group, we embrace a culture of caring, belonging, and trust and enjoy the meaningful connections that come from it: for the whole patient,...
United States - MA - MA - Natick
June 11, 2024
Account Director, Biologics Drug Substance Catalent Biologics is a fast-growing business within Catalent Pharma Solutions focused on providing innovative technologies and solutions to help more and better biologic treatments get to patients. • The business includes our proprietary GPEx cell...
United States - MA - MA - Methuen
June 11, 2024
Account Director, Biologics Drug Substance Catalent Biologics is a fast-growing business within Catalent Pharma Solutions focused on providing innovative technologies and solutions to help more and better biologic treatments get to patients. • The business includes our proprietary GPEx cell...
United States - MA - MA - Framingham
June 11, 2024
Account Director, Biologics Drug Substance Catalent Biologics is a fast-growing business within Catalent Pharma Solutions focused on providing innovative technologies and solutions to help more and better biologic treatments get to patients. • The business includes our proprietary GPEx cell...
United States - MA - MA - Winchester
June 27, 2024
Trustaff Allied is seeking a travel CT Technologist for a travel job in Winchester, Massachusetts. & Requirements • Specialty: CT Technologist • Discipline: Allied Health Professional • Start Date: 07/08/2024 • Duration: 13 weeks • 40 hours per week • Shift: 10 hours, nights • Employment Type:...
United States - MA - MA - Gardner
June 27, 2024
Destination Travelcare is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in Gardner, Massachusetts. & Requirements • Specialty: ED - Emergency Department • Discipline: RN • Start Date: ASAP • Duration: 13 weeks • 36 hours per week • Shift: 12 hours, days • Employment...
United States - MA - MA - DEDHAM
June 27, 2024
AMN Healthcare Allied is seeking a travel Outpatient Physical Therapist for a travel job in DEDHAM, Massachusetts. & Requirements • Specialty: Physical Therapist • Discipline: Therapy • Start Date: 07/30/2024 • Duration: 14 weeks • 40 hours per week • Shift: 8 hours, days • Employment Type: Travel &...
United States - MA - MA - FALL RIVER
June 27, 2024
AMN Healthcare Allied is seeking a travel Physical Therapist for a travel job in FALL RIVER, Massachusetts. & Requirements • Specialty: Physical Therapist • Discipline: Therapy • Start Date: 07/22/2024 • Duration: 13 weeks • 40 hours per week • Shift: 8 hours, days • Employment Type: Travel &...