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Card 4 / 11: Cohort studies do not involve randomization. What advantage does randomization confer to a randomized controlled trial that does not exist in cohort studies?
Answer:
We learned in the session on randomized controlled trials that one of the important advantages of randomization is that it results in two groups that have comparable risk profiles - especially if the trial is a large one. Since cohort studies do not involve randomization, the exposed and unexposed groups may have very different risk profiles. This creates a problem called confounding which we will discuss in more detail in a later session.
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Attribution:
Janet, E.A. Forrester, Kwan Ho Kenneth Chui, Steven Cohen, Michael D. Kneeland, Alice Tang, David Tybor. Epidemiology and Biostatistics 2010. (Tufts University OpenCourseWare), http://ocw.tufts.edu/Course/65/ (Accessed 3 May, 2014). License: Creative Commons BY-NC-SA
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