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Evolution connection

Fight-or-flight response

Interactions of the endocrine hormones have evolved to ensure the body’s internal environment remains stable. Stressors are stimuli that disrupt homeostasis. The sympathetic division of the vertebrate autonomic nervous system has evolved the fight-or-flight response to counter stress-induced disruptions of homeostasis. In the initial alarm phase, the sympathetic nervous system stimulates an increase in energy levels through increased blood glucose levels. This prepares the body for physical activity that may be required to respond to stress: to either fight for survival or to flee from danger.

However, some stresses, such as illness or injury, can last for a long time. Glycogen reserves, which provide energy in the short-term response to stress, are exhausted after several hours and cannot meet long-term energy needs. If glycogen reserves were the only energy source available, neural functioning could not be maintained once the reserves became depleted due to the nervous system’s high requirement for glucose. In this situation, the body has evolved a response to counter long-term stress through the actions of the glucocorticoids, which ensure that long-term energy requirements can be met. The glucocorticoids mobilize lipid and protein reserves, stimulate gluconeogenesis, conserve glucose for use by neural tissue, and stimulate the conservation of salts and water. The mechanisms to maintain homeostasis that are described here are those observed in the human body. However, the fight-or-flight response exists in some form in all vertebrates.

The sympathetic nervous system regulates the stress response via the hypothalamus. Stressful stimuli cause the hypothalamus to signal the adrenal medulla (which mediates short-term stress responses) via nerve impulses, and the adrenal cortex, which mediates long-term stress responses, via the hormone adrenocorticotropic hormone (ACTH)    , which is produced by the anterior pituitary.

Short-term stress response

When presented with a stressful situation, the body responds by calling for the release of hormones that provide a burst of energy. The hormones epinephrine    (also known as adrenaline) and norepinephrine    (also known as noradrenaline) are released by the adrenal medulla. How do these hormones provide a burst of energy? Epinephrine and norepinephrine increase blood glucose levels by stimulating the liver and skeletal muscles to break down glycogen and by stimulating glucose release by liver cells. Additionally, these hormones increase oxygen availability to cells by increasing the heart rate and dilating the bronchioles. The hormones also prioritize body function by increasing blood supply to essential organs such as the heart, brain, and skeletal muscles, while restricting blood flow to organs not in immediate need, such as the skin, digestive system, and kidneys. Epinephrine and norepinephrine are collectively called catecholamines.

Watch this Discovery Channel animation describing the flight-or-flight response.

Questions & Answers

distinguish between anatomy and physiology
Amina Reply
Anatomy is the study of internal structure of an organism while physiology is the study of the function/relationship of the body organs working together as a system in an organism.
adeyeye
distinguish between anatomy and physiology
Erny Reply
regional anatomy is the study of the body regionally
Ismail Reply
what is the meaning of regional anatomy
Aminat Reply
epithelial tissue: it covers the Hollow organs and body cavities
Esomchi Reply
in short way what those epithelial tissue mean
Zainab Reply
in short way what those epithelial tissue mean
Chizoba
What is the function of the skeleton
Lilias Reply
movement
Ogar
Locomotion
Ojo
support
Aishat
and body shape/form
Aishat
what is homeostasis?
Samuel Reply
what's physiology
AminchiSunday Reply
what is physiology
AminchiSunday
physically is the study of the function of the body
Najaatu
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YAU
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YAU
pls what are the main treatment of hiccups
YAU
physiology is the study of the function of the body
Najaatu
hiccups happen when something irritates the nerves that course your diaphragm to contract
Najaatu
how did hypothalamus manege to control all activities of the various hormones
malual
what is protein
Abdulsalam
how can I treat pain a patient feels after eating meals
Namuli Reply
how do I treat a three year old baby of skin infection?
Okocha Reply
It depends on the type of infection. Bacterial, fungal, parasitic or viral?
schler
if you can share the sign ad symptoms of the skin infection then u geh the treatment cox they're different sign ad symptoms of skin infection with different treatment
Sa
the sign and symptoms of maleria
Abdulsalam
prostaglandin and fever
Maha Reply
yes
rayyanu
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rayyanu
prostaglandin E2 is the final mediator.
Lemlem
prostaglandin E2 is the final mediator of fever.
Lemlem
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Agabi
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Jediel
tissue.
Akoi
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Chizoba
Hi
Anya
,good evening
Anya
Discuss the differences between taste and flavor, including how other sensory inputs contribute to our  perception of flavor.
John Reply
taste refers to your understanding of the flavor . while flavor one The other hand is refers to sort of just a blend things.
Faith
While taste primarily relies on our taste buds, flavor involves a complex interplay between taste and aroma
Kamara
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Ummi Reply
omeprazole
Kamara
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Renee
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Kamara
Omeprazole Cimetidine / Tagament For the complicated once ulcer - kit
Patrick
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Nency Reply
Not really sure
Eli
to drain extracellular fluid all over the body.
asegid
The lymphatic system plays several crucial roles in the human body, functioning as a key component of the immune system and contributing to the maintenance of fluid balance. Its main functions include: 1. Immune Response: The lymphatic system produces and transports lymphocytes, which are a type of
asegid
to transport fluids fats proteins and lymphocytes to the blood stream as lymph
Adama
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Source:  OpenStax, Bmcc 103 - concepts of biology. OpenStax CNX. Aug 06, 2015 Download for free at https://legacy.cnx.org/content/col11855/1.2
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