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Case studies of scientists and their “experimental methods”

Francis Bacon (1561-1626): Bacon represents a first step away from sixteenth century thinking, in that he deniedthe validity of empiricism (see introduction) and preferred inductive reasoning (the method of deriving a general “truth” fromobservation of certain similar facts and principles) to the Aristotelian method of deductive reasoning (the method of usinggeneral principles to explain a specific instance, where the particular phenomena is explained through its relation to a“universal truth”). Moreover, like Roger Bacon of the 13th century, Francis Bacon argued that the use of empiricism alone isinsufficient, and thus emphasized the necessity of fact-gathering as a first step in the scientific method, which could then befollowed by carefully recorded and controlled (unbiased) experimentation. Bacon largely differed from his sixteenth centurycounterparts in his insistence that experimentation should not be conducted to simply “see what happens” but “as a way of answeringspecific questions.” Moreover, he believed, as did many of his contemporaries, that a main purpose of science was the bettermentof human society and that experimentation should be applied to hard, real situations rather than to Aristotelian abstract ideas.His experimental method of fact-gathering largely influenced advances in chemistry and biology through the 18th century.

3Hall, p 166, 167

Galileo Galilei (1564-1642): Galileo’s experimental method contrasted with that of Bacon in that hebelieved that the purpose of experimentation should not simply be a means of getting information or of eliminating ignorance, but ameans of testing a theory and of testing the success of the very “testing method.” Galileo argued that phenomena should beinterpreted mechanically, meaning that because every phenomenon results from a combination of the most basic phenomena anduniversal axioms, if one applies the many proven theorems to the larger phenomenon, one can accurately explain why a certainphenomenon occurs the way it does. In other words, he argued that “an explanation of a scientific problem is truly begun when it isreduced to its basic terms of matter and motion,” because only the most basic events occur because of one axiom.

For example, one can demonstrate the concept of “acceleration” in the laboratory with a ball and a slantedboard, but to fullyexplain the idea using Galileo’s reasoning, one would have to utilize the concepts of many different disciplines:the physics-based concepts of time and distance, the idea of gravity, force, and mass, or even the chemical composition of theelement that is accelerating, all of which must be individually broken down to their smallest elements in order for a scientist tofully understand the item as a whole. This “mechanic” or “systemic” approach, while necessitating a mixture of elements from differentdisciplines, also partially removed the burden of fact-gathering emphasized by Bacon. In other words, through Galileo’s method, onewould not observe the phenomenon as a whole, but rather as a construct or system of many existing principles that must be testedtogether, and so gathering facts about the performance of the phenomenon in one situation may not truly lead to an informedobservation of how the phenomenon would occur in a perfect circumstance, when all laws of matter and motion come into play.Galileo’s abstraction of everything concerning the phenomenon except the universal element (e.g. matter or motion) contrastedgreatly with Bacon’s inductive reasoning, but also influenced the work of Descartes, who would later emphasize the importance ofsimplification of phenomena in mathematical terms. Galileo’s experimental method aided advances in chemistry and biology byallowing biologists to explain the work of a muscle or any body function using existing ideas of motion, matter, energy, and otherbasic principles.

Questions & Answers

how does Neisseria cause meningitis
Nyibol Reply
what is microbiologist
Muhammad Reply
what is errata
Muhammad
is the branch of biology that deals with the study of microorganisms.
Ntefuni Reply
What is microbiology
Mercy Reply
studies of microbes
Louisiaste
when we takee the specimen which lumbar,spin,
Ziyad Reply
How bacteria create energy to survive?
Muhamad Reply
Bacteria doesn't produce energy they are dependent upon their substrate in case of lack of nutrients they are able to make spores which helps them to sustain in harsh environments
_Adnan
But not all bacteria make spores, l mean Eukaryotic cells have Mitochondria which acts as powerhouse for them, since bacteria don't have it, what is the substitution for it?
Muhamad
they make spores
Louisiaste
what is sporadic nd endemic, epidemic
Aminu Reply
the significance of food webs for disease transmission
Abreham
food webs brings about an infection as an individual depends on number of diseased foods or carriers dully.
Mark
explain assimilatory nitrate reduction
Esinniobiwa Reply
Assimilatory nitrate reduction is a process that occurs in some microorganisms, such as bacteria and archaea, in which nitrate (NO3-) is reduced to nitrite (NO2-), and then further reduced to ammonia (NH3).
Elkana
This process is called assimilatory nitrate reduction because the nitrogen that is produced is incorporated in the cells of microorganisms where it can be used in the synthesis of amino acids and other nitrogen products
Elkana
Examples of thermophilic organisms
Shu Reply
Give Examples of thermophilic organisms
Shu
advantages of normal Flora to the host
Micheal Reply
Prevent foreign microbes to the host
Abubakar
they provide healthier benefits to their hosts
ayesha
They are friends to host only when Host immune system is strong and become enemies when the host immune system is weakened . very bad relationship!
Mark
what is cell
faisal Reply
cell is the smallest unit of life
Fauziya
cell is the smallest unit of life
Akanni
ok
Innocent
cell is the structural and functional unit of life
Hasan
is the fundamental units of Life
Musa
what are emergency diseases
Micheal Reply
There are nothing like emergency disease but there are some common medical emergency which can occur simultaneously like Bleeding,heart attack,Breathing difficulties,severe pain heart stock.Hope you will get my point .Have a nice day ❣️
_Adnan
define infection ,prevention and control
Innocent
I think infection prevention and control is the avoidance of all things we do that gives out break of infections and promotion of health practices that promote life
Lubega
Heyy Lubega hussein where are u from?
_Adnan
en français
Adama
which site have a normal flora
ESTHER Reply
Many sites of the body have it Skin Nasal cavity Oral cavity Gastro intestinal tract
Safaa
skin
Asiina
skin,Oral,Nasal,GIt
Sadik
How can Commensal can Bacteria change into pathogen?
Sadik
How can Commensal Bacteria change into pathogen?
Sadik
all
Tesfaye
by fussion
Asiina
what are the advantages of normal Flora to the host
Micheal
what are the ways of control and prevention of nosocomial infection in the hospital
Micheal
what is inflammation
Shelly Reply
part of a tissue or an organ being wounded or bruised.
Wilfred
what term is used to name and classify microorganisms?
Micheal Reply
Binomial nomenclature
adeolu
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Source:  OpenStax, Nanotechnology: content and context. OpenStax CNX. May 09, 2007 Download for free at http://cnx.org/content/col10418/1.1
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