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The figures represent the inhalation and expiration process in the human body. It shows the working of the various muscles and the movement of the diaphragm that causes the variation in the pressure inside the lungs.
(a) During inhalation, muscles expand the chest, and the diaphragm moves downward, reducing pressure inside the lungs to less than atmospheric (negative gauge pressure). Pressure between the lungs and chest wall is even lower to overcome the positive pressure created by surface tension in the lungs. (b) During gentle exhalation, the muscles simply relax and surface tension in the alveoli creates a positive pressure inside the lungs, forcing air out. Pressure between the chest wall and lungs remains negative to keep them attached to the chest wall, but it is less negative than during inhalation.

Other pressures in the body

Spinal column and skull

Normally, there is a 5- to12-mm Hg pressure in the fluid surrounding the brain and filling the spinal column. This cerebrospinal fluid serves many purposes, one of which is to supply flotation to the brain. The buoyant force supplied by the fluid nearly equals the weight of the brain, since their densities are nearly equal. If there is a loss of fluid, the brain rests on the inside of the skull, causing severe headaches, constricted blood flow, and serious damage. Spinal fluid pressure is measured by means of a needle inserted between vertebrae that transmits the pressure to a suitable measuring device.

Bladder pressure

This bodily pressure is one of which we are often aware. In fact, there is a relationship between our awareness of this pressure and a subsequent increase in it. Bladder pressure climbs steadily from zero to about 25 mm Hg as the bladder fills to its normal capacity of 500 cm 3 size 12{"500"`"cm" rSup { size 8{3} } } {} . This pressure triggers the micturition reflex    , which stimulates the feeling of needing to urinate. What is more, it also causes muscles around the bladder to contract, raising the pressure to over 100 mm Hg, accentuating the sensation. Coughing, straining, tensing in cold weather, wearing tight clothes, and experiencing simple nervous tension all can increase bladder pressure and trigger this reflex. So can the weight of a pregnant woman's fetus, especially if it is kicking vigorously or pushing down with its head! Bladder pressure can be measured by a catheter or by inserting a needle through the bladder wall and transmitting the pressure to an appropriate measuring device. One hazard of high bladder pressure (sometimes created by an obstruction), is that such pressure can force urine back into the kidneys, causing potentially severe damage.

Pressures in the skeletal system

These pressures are the largest in the body, due both to the high values of initial force, and the small areas to which this force is applied, such as in the joints.. For example, when a person lifts an object improperly, a force of 5000 N may be created between vertebrae in the spine, and this may be applied to an area as small as 10 cm 2 . The pressure created is P = F / A = ( 5000 N ) / ( 10 3 m 2 ) = 5.0 × 10 6 N/m 2 or about 50 atm! This pressure can damage both the spinal discs (the cartilage between vertebrae), as well as the bony vertebrae themselves. Even under normal circumstances, forces between vertebrae in the spine are large enough to create pressures of several atmospheres. Most causes of excessive pressure in the skeletal system can be avoided by lifting properly and avoiding extreme physical activity. (See Forces and Torques in Muscles and Joints .)

Questions & Answers

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In biology, a pathogen (Greek: πάθος pathos "suffering", "passion" and -γενής -genēs "producer of") in the oldest and broadest sense, is anything that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a germ. The term pathogen came into use in the 1880s.[1][2
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biology is the study of life.
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Biology is the study of how living organisms live and survive in a specific environment
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Source:  OpenStax, College physics for ap® courses. OpenStax CNX. Nov 04, 2016 Download for free at https://legacy.cnx.org/content/col11844/1.14
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